The Youth Vascular Consortium
Heart disease remains the leading cause of death worldwide. Prevention of heart disease is a public health priority and identifying individuals at increased risk before symptoms develop is important for minimising disease progression. Vascular ageing, the decline in blood vessel structure and function, is a marker of overall risk on the blood vessels over time and leads to damage in the heart, brain and kidneys. Exposure to environmental and genetic in early life promotes the development and accumulation of blood vessel changes that results in premature or early vascular ageing.
However, research concerning vascular ageing in early life is sparse, despite substantial evidence indicating that the formative years of life play a significant role in contributing to risk observed in adulthood. The international Youth Vascular Consortium (YVC) has been established to investigate the determinants and prognostic value of early vascular ageing from early life. The YVC is a collaborative dataset with rich phenotyping and environmental information.
PhD research question
This project will focus on the determinants (lifestyle, maternal health and socioeconomic impact) of early vascular ageing in children, adolescents and young adults. However, there are a number of research questions that can be explored within the YVC and projects can be shaped to meet the student’s interests.
This PhD project will be predominantly based on retrospectively collected data. Students will be expected to have some experience in epidemiology, statistical analysis and an interest in big data.
Menzies Institute for Medical Research, University of Tasmania. Hobart, Australia.
This project can be commenced from outside of Australia.
Dr Rachel Climie (Rachel.Climie@utas.edu)
A/Prof Seana Gall (Seana.Gall@utas.edu.au)
Interested students are encouraged to contact the supervisors.
For further information, click here.